Metabolic syndrome is characterized by cardio-metabolic risk factors that include obesity, insulin resistance, hypertension and dyslipidemia. Oxidative stress is known to play a major role in the pathogenesis of metabolic syndrome. The objective of this study was to examine the effectiveness of hydrogen rich water (1.5–2 L/day), 8-week study on 20 subjects with potential metabolic syndrome. Hydrogen rich water was produced, by placing a Alkaline stick into drinking water, by the following chemical reaction:
Mg + 2H2O → Mg (OH)2 + H2.
The consumption of hydrogen rich water for 8 weeks resulted in a 39% increase in antioxidant enzyme superoxide dismutase (SOD). Further, subjects demonstrated an 8% increase in high density lipoprotein (HDL)-cholesterol and a 13% decrease in total cholesterol/HDL-cholesterol from baseline to week 4. In conclusion, drinking hydrogen rich water represents a potentially novel therapeutic and preventive strategy for metabolic syndrome. The portable alkaline stick was a safe, easy and effective method of delivering hydrogen rich water for daily consumption by participants in the study.